Flu Widespread, Leading a Range of Winter’s Ills





It is not your imagination — more people you know are sick this winter, even people who have had flu shots.




The country is in the grip of three emerging flu or flulike epidemics: an early start to the annual flu season with an unusually aggressive virus, a surge in a new type of norovirus, and the worst whooping cough outbreak in 60 years. And these are all developing amid the normal winter highs for the many viruses that cause symptoms on the “colds and flu” spectrum.


Influenza is widespread, and causing local crises. On Wednesday, Boston’s mayor declared a public health emergency as cases flooded hospital emergency rooms.


Google’s national flu trend maps, which track flu-related searches, are almost solid red (for “intense activity”) and the Centers for Disease Control and Prevention’s weekly FluView maps, which track confirmed cases, are nearly solid brown (for “widespread activity”).


“Yesterday, I saw a construction worker, a big strong guy in his Carhartts who looked like he could fall off a roof without noticing it,” said Dr. Beth Zeeman, an emergency room doctor for MetroWest Medical Center in Framingham, Mass., just outside Boston. “He was in a fetal position with fever and chills, like a wet rag. When I see one of those cases, I just tighten up my mask a little.”


Massachusetts General Hospital in Boston started asking visitors with even mild cold symptoms to wear masks and to avoid maternity wards. The hospital has treated 532 confirmed influenza patients this season and admitted 167, even more than it did by this date during the 2009-10 swine flu pandemic.


At Brigham and Women’s Hospital, 100 patients were crowded into spaces licensed for 53. Beds lined halls and pressed against vending machines. Overflow patients sat on benches in the lobby wearing surgical masks.


“Today was the first time I think I was experiencing my first pandemic,” said Heidi Crim, the nursing director, who saw both the swine flu and SARS outbreaks here. Adding to the problem, she said, many staff members were at home sick and supplies like flu test swabs were running out.


Nationally, deaths and hospitalizations are still below epidemic thresholds. But experts do not expect that to remain true. Pneumonia usually shows up in national statistics only a week or two after emergency rooms report surges in cases, and deaths start rising a week or two after that, said Dr. Gregory A. Poland, a vaccine specialist at the Mayo Clinic in Minnesota. The predominant flu strain circulating is an H3N2, which typically kills more people than the H1N1 strains that usually predominate; the relatively lethal 2003-4 “Fujian flu” season was overwhelmingly H3N2.


No cases have been resistant to Tamiflu, which can ease symptoms if taken within 48 hours, and this year’s flu shot is well-matched to the H3N2 strain, the C.D.C. said. Flu shots are imperfect, especially in the elderly, whose immune systems may not be strong enough to produce enough antibodies.


Simultaneously, the country is seeing a large and early outbreak of norovirus, the “cruise ship flu” or “stomach flu,” said Dr. Aron J. Hall of the C.D.C.’s viral gastroenterology branch. It includes a new strain, which first appeared in Australia and is known as the Sydney 2012 variant.


This week, Maine’s health department said that state was seeing a large spike in cases. Cities across Canada reported norovirus outbreaks so serious that hospitals were shutting down whole wards for disinfection because patients were getting infected after moving into the rooms of those who had just recovered. The classic symptoms of norovirus are “explosive” diarrhea and “projectile” vomiting, which can send infectious particles flying yards away.


“I also saw a woman I’m sure had norovirus,” Dr. Zeeman said. “She said she’d gone to the bathroom 14 times at home and 4 times since she came into the E.R. You can get dehydrated really quickly that way.”


This month, the C.D.C. said the United States was having its biggest outbreak of pertussis in 60 years; there were about 42,000 confirmed cases, the highest total since 1955. The disease is unrelated to flu but causes a hacking, constant cough and breathlessness. While it is unpleasant, adults almost always survive; the greatest danger is to infants, especially premature ones with undeveloped lungs. Of the 18 recorded deaths in 2012, all but three were of infants under age 1.


That outbreak is worst in cold-weather states, including Colorado, Washington, Wisconsin, Minnesota and Vermont.


Although most children are vaccinated several times against pertussis, those shots wear off with age. It is possible, the authorities said, that a new, safer vaccine introduced in the 1990s gives protection that does not last as long, so more teenagers and adults are vulnerable.


And, Dr. Poland said, if many New Yorkers are catching laryngitis, as has been reported, it is probably a rhinovirus. “It’s typically a sore, really scratchy throat, and you sometimes lose your voice,” he said.


Though flu cases in New York City are rising rapidly, the city health department has no plans to declare an emergency, largely because of concern that doing so would drive mildly sick people to emergency rooms, said Dr. Jay K. Varma, deputy director for disease control. The city would prefer people went to private doctors or, if still healthy, to pharmacies for flu shots. Nursing homes have had worrisome outbreaks, he said, and nine elderly patients have died. Homes need to be more alert, vaccinate patients, separate those who fall ill and treat them faster with antivirals, he said.


Dr. Susan I. Gerber of the C.D.C.’s respiratory diseases branch, said her agency has not seen any unusual spike of rhinovirus, parainfluenza, adenovirus, coronavirus or the dozens of other causes of the “common cold,” but the country is having its typical winter surge of some, like respiratory syncytial virus “that can mimic flulike symptoms, especially in young children.”


The C.D.C. and the local health authorities continue to advocate getting flu shots. Although it takes up to two weeks to build immunity, “we don’t know if the season has peaked yet,” said Dr. Joseph Bresee, chief of prevention in the agency’s flu division.


Flu shots and nasal mists contain vaccines against three strains, the H3N2, the H1N1 and a B. Thus far this season, Dr. Bresee said, H1N1 cases have been rare, and the H3N2 component has been a good match against almost all the confirmed H3N2 samples the agency has tested.


About a fifth of all flus this year thus far are from B strains. That part of the vaccine is a good match only 70 percent of the time, because two B’s are circulating.


For that reason, he said, flu shots are being reformulated. Within two years, they said, most will contain vaccines against both B strains.


Joanna Constantine, 28, a stylist at the Guy Thomas Hair Salon on West 56th Street in Manhattan, said she recently was so sick that she was off work and in bed for five days — and silenced by laryngitis for four of them.


She did not have the classic flu symptoms — a high fever, aches and chills — so she knew it was probably something else.


Still, she said, it scared her enough that she will get a flu shot next year. She had not bothered to get one since her last pregnancy, she said. But she has a 7-year-old son and a 5-year-old daughter, “and my little guys get theirs every year.”


Jess Bidgood contributed reporting.



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Google Chief Urges North Korea to Embrace WebGoogle Chief Urges North Korea to Embrace Web





BEIJING — Eric E. Schmidt, the executive chairman of Google, returned from a four-day visit to North Korea on Thursday with a message for the reclusive nation’s young new leader: embrace the Web or else.




Mr. Schmidt, part of private delegation led by former Gov. Bill Richardson of New Mexico that also sought to press North Korea on humanitarian and diplomatic issues, said North Korea risked falling further behind if it did not provide more access to cellphone service and the Internet.


“As the world becomes increasingly connected, their decision to be virtually isolated is very much going to affect their physical world, their economic growth and so forth and it will make it harder for them to catch up economically,” he told reporters during a stop at Beijing International Airport. “We made that alternative very, very clear.”


Their visit, the highest-profile delegation of Americans since Kim Jong-un took power upon the death of his father in December 2011, comes at precarious time for United States-North Korean relations after the North’s rocket launch last month that drew international condemnation. North Korea insists its Unha-3 rocket is part of a peaceful space program; South Korean and American intelligence officials say the North was testing a long-range ballistic missile that could one day reach the United States.


The State Department was not thrilled with Mr. Richardson’s freelance diplomacy, at least not publicly. A spokeswoman described Mr. Richardson’s visit as not “particularly helpful” given that the United States is seeking to rally support for tougher international sanctions against the North. Some North Korea experts have characterized the self-described humanitarian mission as naïve, saying it will ultimately serve the North’s propaganda needs.


Although Mr. Richardson did not address the criticism on Thursday, he said his hosts were receptive during discussions about ways to reduce tensions on the Korean peninsula as well as his effort to seek the release of a Korean-American who was detained in November in the north of the country.


“We had a very positive reaction,” Mr. Richardson said.


The delegation did not meet with the detained American, Kenneth Bae, 44, a tour operator from Washington who has been accused of “hostile acts,” but Mr. Richardson said he was assured Mr. Bae was being treated well and that judicial proceedings would begin soon.


There was one tangible success of their visit: the authorities, Mr. Richardson said, had agreed to deliver to Mr. Bae a letter from his son.


But Mr. Richardson’s efforts to promote peace, love and understanding were overshadowed by the billion-dollar wattage of Mr. Schmidt, a vocal proponent of Internet freedom. The delegation, which included Mr. Schmidt’s daughter and Jared Cohen, a former State Department official who heads Google Ideas, the company’s research arm, made highly choreographed visits to several sites meant to display the nation’s information technology prowess.


At the elite Kim Il Sung University, computer science students showed off their ability to surf the Internet, stopping on a Web site run by Cornell University.


For most North Koreans, using a computer, let alone accessing Google, is all but impossible. Although the country has global broadband Internet, few people are allowed to use it, and if they do, their surfing is strictly monitored. Experts say fewer than a thousand people have such access, most of them software developers, government officials and well-connected party loyalists.


At the main library in the North Korean capital, Pyongyang, the Grand People’s Study House, the Americans watched as users in thick winter coats crowded around computer screens that connect to North Korea’s Intranet, known as Kwangmyong, which serves up government-approved documents, books and archival newspapers.


They later toured the Korea Computer Center, an incubator for domestic software and hardware, where they played with a homegrown tablet and other gadgetry, most of it developed with help from Russia, China and India. A quote from Kim Jong Il, the current leader’s father, graced the room: “Now is the era for science and technology. It is the era of computers.”


Since he came to power, the 20-something Mr. Kim, who was educated in a Swiss boarding school, has emphasized the importance of science and technology for economic development. And while he has called for computerizing in the nation’s dilapidated factories — and spending even more scarce hard currency on developing ballistic missiles — he has made no mention of addressing North Korea’s status as one of the world’s least wired nations.


Mr. Schmidt appears to have learned a great deal from his visit. Speaking to reporters in Beijing, he talked in some detail about the nation’s 3G cellular phone service, developed by the Egyptian telecom company Orascom. But he noted with disappointment that little more than one million of the country’s 24 million citizens had cellphones.


That system, he added hopefully, had the potential to provide Internet access but that so far the feature was unavailable. “It would be very easy for them to turn it on,” he said.


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India Ink: The Delhi Gang Rape Accused: Vinay Sharma, a 'Quiet and Simple' Boy

To keep her children warm on Wednesday night, Champa Devi tried to get a small fire going by puffing air into four pieces of wood outside their home in a South Delhi slum.

“I am heartbroken,” she said, coughing as a cloud of smoke billowed around her. “When I wake up, it feels like my heart has been torn away.”

Ms. Champa, 37, is the mother of Vinay Sharma, one of the six accused in the gang rape of a 23-year-old woman on a moving bus on Dec. 16, which resulted in her death two weeks later.

The horrific account of the rape, in which attackers beat their victim and her male companion with an iron rod and threw them naked onto a highway, sent shock waves through India.

Ms. Champa said she still can’t fathom how her son, who she says was born in March 1994, could have been involved in the gruesome crime. “He was always a quiet and simple boy,” she said. “He worked hard in school and always got top marks,” she said. “He especially liked studying English. We hoped for a good job in the future.”

Mr. Sharma, his family said, had grown up to be serious-minded man who recently registered for college. He earned 3,000 rupees, or about $54, a month as a handyman in a gym. The money went mostly to support the meager wages of his father, who works as a laborer.

The Sharma household is in the Ravidas slum, where four of the six accused lived, according to police. The slum, made up of about 300 houses, is maze of muddy alleys, next to the Bijri Khan tomb, a monument from the 15th century Lodhi dynasty.

On an early Wednesday visit to the Sharma home, no one responded to a few initial knocks on their door. “Leave them alone — haven’t they suffered for losing their son?” cried an elderly woman standing in the narrow lane. “Now what are they to do except be hounded by you media people?”

Hearing the commotion, a teenage girl emerged from a nearby house and first identified herself as a neighbor. “He was a really good guy who was led astray,” she said about Mr. Sharma. But the emotions on her face betrayed her, and she quickly admitted to being Manju Sharma, his sister. The 14-year-old, who has burn marks on her face, described her brother as deeply caring about his three siblings.

“After I was burned as a baby, he always made sure I stayed away from the stove,” she said. “As kids, he used to gently pinch me on my feet and he often played hide-and-seek with our small brother.” Ms. Sharma said that her brother also paid for the medicines needed to treat her diabetes.

Later in the evening, the accused’s mother agreed to an interview. She said that she had spent the day standing in a long hospital line to get her daughter’s medicine. Without a regular dosage, she faints and can’t attend school, she said.

“It costs 100 rupees a week and we can’t afford it without Vinay,” said Ms. Champa. “Without him, how will get the girls married?”

While it isn’t surprising for Mr. Sharma’s family to speak well of him, his neighbors and friends give similar accounts.

“I’ve known Vinay since he was a boy and played with my children,” said a middle-aged shopkeeper in the slum, who declined to give her name to avoid any further media attention. “He just isn’t the kind to make trouble.”

Anil, 14, who declined to give his last name, recalled his friend had only one interest: cricket. “When Vinay wasn’t at work, he would play some fun matches,” he said.

A short distance from the slum, another middle-aged woman who knew the family agreed to speak on the condition of anonymity to avoid upsetting them. She said she hoped none of the four men returned.

“Vinay may have been a good boy, but now even he can’t be trusted,” she said. “As a woman, I wouldn’t feel safe. What if they tried something on me?”

Mr. Sharma confessed to beating up the woman’s male friend in a December court appearance and asked to be hanged, according to local media reports. He and another defendant, Pawan Kumar, a fruit seller from the same slum, also volunteered to become witnesses for the government, a Delhi police official said.

Mr. Sharma’s friends and neighbors say they blame Ram Singh and Mukesh Singh, two brothers who are also accused in the rape case, for leading the other men astray.

Some residents of the Ravidas neighborhood said they clearly remembered the night of Dec. 16, and that they sensed that Ram and Mukesh Singh, who also lived in the area, were in a mood to make trouble after they had drunk alcohol.

Ms. Sharma said that her brother was playing marbles with the neighborhood children. When it grew dark, his mother recalled, he came into the house and watched television.

“He was eating a sweet bun and laughing over cartoons with his siblings,” she said. “Then, the fruit seller boy came to call him and he left,” she said. “That was the last time I saw him.”

India Ink is profiling the men accused in the Delhi gang rape case. This is the second. Read the first here.

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DealBook: Former Analyst Cooperates in Insider Trading Case

A former analyst at SAC Capital Advisors, the hedge fund owned by the billionaire investor Steven A. Cohen, has given federal agents the names of about 20 people he said had engaged in insider trading, according to a court filing.

The disclosure of the extraordinary cooperation by the former SAC analyst, Wesley Wang, emerged in a pleading filed by federal prosecutors. In a letter to a judge, the government credited Mr. Wang with substantial assistance in its broad insider trading crackdown.

In addition to the 20 names, the government said information provided by Mr. Wang had contributed to the criminal convictions of more than 10 people.

Hedge Fund Inquiry

The letter, which was filed in connection with Mr. Wang’s sentencing, named 12 individuals who have already been charged or identified in public as part of the investigation. But the section that gave specifics about Mr. Wang’s help — and named other people, according to a person with knowledge of the letter — was heavily redacted.

Prosecutors emphasized that Mr. Wang’s help was still yielding fruit.

“The full extent of Wang’s information and cooperation remains to be fully realized,” the government said in the filing. “Even taking into account what has been developed to date, it is exceptional.”

Prosecutors praised Mr. Wang’s assistance in advance of the sentencing, which is scheduled for Wednesday afternoon in Federal District Court in Manhattan. They urged Judge Jed. S. Rakoff to hand down a lenient sentence. Government cooperators have been vital to prosecutors in the insider trading investigation, which has resulted in the guilty pleas or convictions of more than 70 individuals since mid-2009.

A lawyer for Mr. Wang, Michael Celio, declined to comment.

Mr. Wang is one of a number of former traders and analysts previously associated with SAC Capital, which manages $14 billion and has one of the best investment track records on Wall Street. At least six former SAC employees have been tied to insider trading while at the fund, which is based in Stamford, Conn. The most recent case — an indictment of a former SAC portfolio manager, Mathew Martoma — connects Mr. Cohen to questionable trades.

Mr. Cohen and SAC have not been charged with any wrongdoing, and Mr. Cohen has told his employees and clients that he believes he and the firm acted appropriately at all times. The Securities and Exchange Commission has warned SAC that it may file a civil action against the firm in connection with the Martoma case.

The case against Mr. Wang, a journeyman hedge fund analyst who spent just a couple of years at SAC nearly a decade ago, has largely gone unnoticed.

A native of Taiwan, Mr. Wang, 39, of Berkeley, Calif., worked as a technology stock analyst at the SAC unit Sigma Capital from 2002 to 2005. The F.B.I. first learned about Mr. Wang’s insider trading in 2008 from another cooperator. Agents approached him in early 2009 and he almost immediately began cooperating, agreeing to wear a wire in meetings and also recording telephone conversations with his Wall Street and corporate contacts.

“While these meetings caused Mr. Wang considerable stress, he nonetheless maintained his composure throughout them,” the prosecutors wrote in the sentencing letter.

Last summer, Mr. Wang appeared in a federal court and entered a guilty plea, admitting to leaking confidential information about technology stocks to a former Sigma portfolio manager, Dipak Patel, and to the former head of Whitman Capital, Douglas F. Whitman.

A jury convicted Mr. Whitman in August. He has yet to be sentenced. The government has not charged Mr. Patel.

Mr. Wang testified at Mr. Whitman’s trial. He said that he obtained inside information about Cisco Systems and passed it on to Mr. Whitman, who in turn shared secret data about other companies.

In the sentencing letter, prosecutors said the information provided by Mr. Wang led to their being able to approach certain other people who then also agreed to cooperate. They included Karl Motey, a crucial figure in the government’s extensive investigation into expert network firms — middlemen connecting traders to public company employees — that led to dozens of convictions.

Prosecutors emphasized that they still had plenty of work to do with all of the information supplied to them by Mr. Wang, and requested that his continued cooperation be made a condition of his sentencing.

“Wang has also identified a number of individuals involved in insider trading whom the F.B.I. has not yet approached and/or whom the government has not yet charged,” the letter said.

A version of this article appeared in print on 01/09/2013, on page B1 of the NewYork edition with the headline: Ex-Analyst Cooperates In Insider Trade Case.
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Gaps Seen in Therapy for Suicidal Teenagers





Most adolescents who plan or attempt suicide have already received at least some mental health treatment, raising questions about the effectiveness of current approaches to helping troubled youths, according to the largest in-depth analysis to date of suicidal behaviors in American teenagers.




The study, in the journal JAMA Psychiatry, found that 55 percent of suicidal teenagers had received some therapy before they thought about suicide, planned it or tried to kill themselves, contradicting the widely held belief that suicide is due in part to a lack of access to treatment.


The findings, based on interviews with a nationwide sample of more than 6,000 teenagers and at least one parent of each, linked suicidal behavior to complex combinations of mood disorders like depression and behavior problems like attention-deficit and eating disorders, as well as alcohol and drug abuse.


The study found that about one in eight teenagers had persistent suicidal thoughts at some point, and that about a third of those who had suicidal thoughts had made an attempt, usually within a year of having the idea.


Previous studies have had similar findings, based on smaller, regional samples. But the new study is the first to suggest, in a large nationwide sample, that access to treatment does not make a big difference.


The study suggests that effective treatment for severely suicidal teenagers must address not just mood disorders, but also behavior problems that can lead to impulsive acts, experts said. According to the Centers for Disease Control and Prevention, 1,386 people between the ages of 13 and 18 committed suicide in 2010, the latest year for which numbers are available.


“I think one of the take-aways here is that treatment for depression may be necessary but not sufficient to prevent kids from attempting suicide,” said Dr. David Brent, a professor of psychiatry at the University of Pittsburgh, who was not involved in the study. “We simply do not have empirically validated treatments for recurrent suicidal behavior.”


The report said nothing about whether the therapies given were state of the art or carefully done, said Matt Nock, a professor of psychology at Harvard and the lead author, and it is possible that some of the treatments prevented suicide attempts. “But it’s telling us we’ve got a long way to go to do this right,” Dr. Nock said. His co-authors included Ronald C. Kessler of Harvard and researchers from Boston University and Children’s Hospital Boston.


Margaret McConnell, a consultant in Alexandria, Va., said her daughter Alice, who killed herself in 2006 at the age of 17, was getting treatment at the time. “I think there might have been some carelessness in the way the treatment was done,” Ms. McConnell said, “and I was trusting a 17-year-old to manage her own medication. We found out after we lost her that she wasn’t taking it regularly.”


In the study, researchers surveyed 6,483 adolescents from the ages of 13 to 18 and found that 9 percent of male teenagers and 15 percent of female teenagers experienced some stretch of having persistent suicidal thoughts. Among girls, 5 percent made suicide plans and 6 percent made at least one attempt (some were unplanned).


Among boys, 3 percent made plans and 2 percent carried out attempts, which tended to be more lethal than girls’ attempts.


(Suicidal thinking or behavior was virtually unheard-of before age 10.)


Over all, about one-third of teenagers with persistent suicidal thoughts went on to make an attempt to take their own lives.


Almost all of the suicidal adolescents in the study qualified for some psychiatric diagnosis, whether depression, phobias or generalized anxiety disorder. Those with an added behavior problem — attention-deficit disorder, substance abuse, explosive anger — were more likely to act on thoughts of self-harm, the study found.


Doctors have tested a range of therapies to prevent or reduce recurrent suicidal behaviors, with mixed success. Medications can ease depression, but in some cases they can increase suicidal thinking. Talk therapy can contain some behavior problems, but not all.


One approach, called dialectical behavior therapy, has proved effective in reducing hospitalizations and suicide attempts in, among others, people with borderline personality disorder, who are highly prone to self-harm.


But suicidal teenagers who have a mixture of mood and behavior issues are difficult to reach. In one 2011 study, researchers at George Mason University reduced suicide attempts, hospitalizations, drinking and drug use among suicidal adolescent substance abusers. The study found that a combination of intensive treatments — talk therapy for mood problems, family-based therapy for behavior issues and patient-led reduction in drug use — was more effective than regular therapies.


“But that’s just one study, and it’s small,” said Dr. Brent of the University of Pittsburgh. “We can treat components of the overall problem, but that’s about all.”


Ms. McConnell said that her daughter’s depression had seemed mild and that there was no warning that she would take her life. “I think therapy does help a lot of people, if it’s handled right,” she said.


Read More..

Gaps Seen in Therapy for Suicidal Teenagers





Most adolescents who plan or attempt suicide have already received at least some mental health treatment, raising questions about the effectiveness of current approaches to helping troubled youths, according to the largest in-depth analysis to date of suicidal behaviors in American teenagers.




The study, in the journal JAMA Psychiatry, found that 55 percent of suicidal teenagers had received some therapy before they thought about suicide, planned it or tried to kill themselves, contradicting the widely held belief that suicide is due in part to a lack of access to treatment.


The findings, based on interviews with a nationwide sample of more than 6,000 teenagers and at least one parent of each, linked suicidal behavior to complex combinations of mood disorders like depression and behavior problems like attention-deficit and eating disorders, as well as alcohol and drug abuse.


The study found that about one in eight teenagers had persistent suicidal thoughts at some point, and that about a third of those who had suicidal thoughts had made an attempt, usually within a year of having the idea.


Previous studies have had similar findings, based on smaller, regional samples. But the new study is the first to suggest, in a large nationwide sample, that access to treatment does not make a big difference.


The study suggests that effective treatment for severely suicidal teenagers must address not just mood disorders, but also behavior problems that can lead to impulsive acts, experts said. According to the Centers for Disease Control and Prevention, 1,386 people between the ages of 13 and 18 committed suicide in 2010, the latest year for which numbers are available.


“I think one of the take-aways here is that treatment for depression may be necessary but not sufficient to prevent kids from attempting suicide,” said Dr. David Brent, a professor of psychiatry at the University of Pittsburgh, who was not involved in the study. “We simply do not have empirically validated treatments for recurrent suicidal behavior.”


The report said nothing about whether the therapies given were state of the art or carefully done, said Matt Nock, a professor of psychology at Harvard and the lead author, and it is possible that some of the treatments prevented suicide attempts. “But it’s telling us we’ve got a long way to go to do this right,” Dr. Nock said. His co-authors included Ronald C. Kessler of Harvard and researchers from Boston University and Children’s Hospital Boston.


Margaret McConnell, a consultant in Alexandria, Va., said her daughter Alice, who killed herself in 2006 at the age of 17, was getting treatment at the time. “I think there might have been some carelessness in the way the treatment was done,” Ms. McConnell said, “and I was trusting a 17-year-old to manage her own medication. We found out after we lost her that she wasn’t taking it regularly.”


In the study, researchers surveyed 6,483 adolescents from the ages of 13 to 18 and found that 9 percent of male teenagers and 15 percent of female teenagers experienced some stretch of having persistent suicidal thoughts. Among girls, 5 percent made suicide plans and 6 percent made at least one attempt (some were unplanned).


Among boys, 3 percent made plans and 2 percent carried out attempts, which tended to be more lethal than girls’ attempts.


(Suicidal thinking or behavior was virtually unheard-of before age 10.)


Over all, about one-third of teenagers with persistent suicidal thoughts went on to make an attempt to take their own lives.


Almost all of the suicidal adolescents in the study qualified for some psychiatric diagnosis, whether depression, phobias or generalized anxiety disorder. Those with an added behavior problem — attention-deficit disorder, substance abuse, explosive anger — were more likely to act on thoughts of self-harm, the study found.


Doctors have tested a range of therapies to prevent or reduce recurrent suicidal behaviors, with mixed success. Medications can ease depression, but in some cases they can increase suicidal thinking. Talk therapy can contain some behavior problems, but not all.


One approach, called dialectical behavior therapy, has proved effective in reducing hospitalizations and suicide attempts in, among others, people with borderline personality disorder, who are highly prone to self-harm.


But suicidal teenagers who have a mixture of mood and behavior issues are difficult to reach. In one 2011 study, researchers at George Mason University reduced suicide attempts, hospitalizations, drinking and drug use among suicidal adolescent substance abusers. The study found that a combination of intensive treatments — talk therapy for mood problems, family-based therapy for behavior issues and patient-led reduction in drug use — was more effective than regular therapies.


“But that’s just one study, and it’s small,” said Dr. Brent of the University of Pittsburgh. “We can treat components of the overall problem, but that’s about all.”


Ms. McConnell said that her daughter’s depression had seemed mild and that there was no warning that she would take her life. “I think therapy does help a lot of people, if it’s handled right,” she said.


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A Financial Service for People Fed Up With Banks


Steve Dykes for The New York Times


Shamir Karkal, left, and Josh Reich, center, the founders of Simple.







Like many people, Josh Reich got fed up with his bank after it charged him overdraft fees and he endured painful customer service calls to fight them. But unlike most people, Mr. Reich, a software engineer from Australia, decided to come up with a better way to bank.




Mr. Reich and a co-founder, Shamir Karkal, created Simple, an online banking start-up company based in Portland, Ore., that offers its customers free checking accounts and data-rich analysis of their transactions and spending habits.


Few entrepreneurs dare to set their sights on industries as large and entrenched as banking and expect to flourish. But Mr. Reich, 34, a professed data nerd who has built computers and tinkered with the innards of sophisticated cameras, holds a master’s degree in business and has a robust background in financial data analysis. He is confident that Simple’s minimalist approach — it promises not to charge any fees for any services — will draw fans and customers.


“Banks make money by keeping customers confused,” Mr. Reich said. “There’s no incentives to make the experience better.”


Of course, inviting people to trust a start-up with their money is a lot to ask. The company, which began signing up customers late last year in a deliberately slow fashion, now has 20,000 and has processed transactions worth more than $200 million.


It also has the backing of prominent venture capital firms including Shasta Ventures, SV Angel and IA Ventures and has raised more than $13 million. Simple has few, if any, direct competitors, although some services like SmartyPig and Mint offer analysis of bank accounts and financial transactions.


Simple is actually not a bank. It has deals with CBW Bank and Bancorp, federally insured banks, to hold its customers’ money.


And it has built slick apps for the Web and mobile devices to give customers an overview of their accounts and transactions. But it encourages customers to treat it as a bank, closing their more traditional accounts and only using Simple.


The company’s biggest challenge, banking analysts say, will be to persuade people to give it a try.


“It is extremely difficult to get consumers to change and leave their banks,” said Jacob Jegher, an analyst at Celent, a research and consulting firm. “Plus, although they are not a bank, they still operate like a financial institution, and they will face challenges that big banks have decades of experience with.”


After the financial crisis, smaller community banks and credit unions gained customers eager for alternatives to larger corporate banks. Experts say Simple could attract those customers as well.


Early adopters are warming to the service; during a speech last fall at a conference aimed at technology enthusiasts, designers and creative people, Mr. Reich asked how many in attendance were Simple customers. A majority of the crowd raised hands.


Mr. Reich said Simple was keeping its first group of customers small to allow it to work out any kinks. (Already there have been some flaws, like one that briefly locked several users out of their accounts in November.) At this stage, those who want a Simple account have to request an invitation on its site, though these are handed out fairly liberally to those who meet the minimal qualifications of Simple and its bank partners.


Customers receive a plain white card that can be used like a debit card. The company offers most traditional banking features, like direct deposit and money transfers. But there is plenty it does not offer, like joint or business checking accounts, or paper checkbooks, which may be a deal killer for some.


The start-up does not have physical bank branches or automated teller machines, nor does it plan to build any. As a result, Simple customers cannot make cash deposits and must rely on the Internet and phone for service.


Simple tries to make up for what it does not have with modern software design and data analysis.


Each Simple transaction is tagged with detailed information that allows customers to search their accounts with plain English commands like “Show me how much I spent on meals over $30 last month,” or “Show me how much money I spent on gifts in December.”


Customers can see transactions plotted on a map or search for all transactions in a particular state or country, something that would be difficult with a traditional bank account.


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Record Heat Fuels Widespread Fires in Australia


Lukas Coch/European Pressphoto Agency


Firefighters battled a grass fire in Oura, near Wagga Wagga, Australia, on Tuesday. On Monday, Australia’s hottest day on record, the national average was 104.59 degrees.







SYDNEY, Australia — Australia on Wednesday was grappling with an unprecedented heat wave that has sparked raging bushfires across some of the country’s most populated regions — pushing firefighters to their limits, residents to their wits’ end and leaving meteorologists tracking the soaring temperatures into uncharted territory.




Four months of record-breaking temperatures stretching back to September of last year have combined over the past week with widespread drought conditions and high winds to create what the government had labeled “catastrophic” fire conditions along the heavily populated eastern and southeastern coasts of the country, where much of the population is centered.


Data analyzed on Wednesday by the government-run Bureau of Meteorology indicated that national heat records had again been set — Tuesday was the third hottest day on record at 40 Celsius (104 Fahrenheit) and the mean national temperature average was the highest in history, breaking a record set just the day before, on Monday. Meteorologists have taken the extraordinary step of adding two new colors to its temperature charts to extend their range to 54 degrees Celsius (129 Fahrenheit) from the previous cap of 50 degrees Celsius (122 Fahrenheit) to account for the climbing temperatures.


“If you look at yesterday, at Australia as a whole, it was the hottest day in our records going back to 1911,” said David Jones, manager of climate monitoring prediction at the Bureau of Meteorology. “From this national perspective, one might say this is the largest heat event in the country’s recorded history.”


With the record-breaking heat, firefighters were struggling to contain the huge bushfires in Australia’s most populous state, New South Wales, which have swallowed around 500 square miles of forest and farmland since they erupted on Tuesday. Fires on the island state of Tasmania off the country’s southern coast have destroyed more than 300 square miles since Friday.


No deaths have been reported in connection with the fires, although about 100 people remain unaccounted for since a fire destroyed around 90 homes in the Tasmanian town of Dunalley, east of the state capital of Hobart, last week.


Thousands of head of cattle and sheep are believed to have died already in the fires, which have torn through some of the country’s most productive agricultural and farming regions. Some 10,000 sheep alone are believed to have died in New South Wales, according to the state government’s Department of Primary Industries.


Despite a brief respite from the searing heat in some coastal areas on Wednesday, the government has warned that the hot spell was only just getting started as the so-called “Dome of Heat” began moving up the eastern seaboard away from Sydney, where it was expected to deliver more blistering weather to Brisbane, Australia’s third largest city.


NASA published alarming photographs of the enormous fires, which have grown so large that they are visible from outer space, allowing them to be photographed from the International Space Station on Tuesday. The intensity of the bushfires and the unrelenting nature of the heat have already led some climate scientists to criticize what they see as an indifference to the realities of man-made climate change, which is widely believed to be the driving factor behind these events.


“Those of us who spend our days trawling — and contributing to — the scientific literature on climate change are becoming increasingly gloomy about the future of human civilization,” Elizabeth Hanna, a researcher at the Australian National University in Canberra, told The Sydney Morning Herald. “We are well past the time of niceties, of avoiding the dire nature of what is unfolding, and politely trying not to scare the public.”


Dr. Jones, the government climate scientist, echoed that opinion.


“This event is turning out to be hotter, more spatially expansive and the duration is quite remarkable,” he said in an interview. “And that suggests climate change.”


At least 141 fires continued to rage in New South Wales on Wednesday, with 31 of those fires burning out of control. The deputy commissioner of the state’s Rural Fire Service, Rob Rogers, told reporters that it was a bad sign that the fires could not be contained during the brief drop in temperatures.


“We’ve got a huge swath of New South Wales that potentially is going to get new fires again this afternoon,” Mr. Rogers said. “It will be an absolute battle to get containment on most of those fires before the return of the hot weather on the weekend.”


Tuesday’s new high adds to a growing list of records the Bureau of Meteorology has recorded during this extended heat wave: the first time the country has recorded seven consecutive days of temperatures above 39 degrees Celsius (102 degrees Fahrenheit); the year with the most record hot days in Australia since national records began in 1910, and nationwide average temperatures on each of the first eight days of 2013 that were among the top 20 hottest days on record here.


Dr. Jones warned that there was no sign that temperatures would stay down even as the heat wave appeared to slightly recede in Sydney on Wednesday.


“We expect it to stay very hot across inland Australia for the next week,” he said. “Beyond that it’s hard to say.”


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Wall Street Trades Lower as Earnings Reports Begin





Stocks trading on Wall Street ticked lower on Tuesday as an earnings season that is expected to show sluggish corporate growth got under way.


The Standard & Poor’s 500-stock index fell 0.4 percent in morning trading, the Dow Jones industrial average lost 0.4 percent and the Nasdaq composite index fell 0.2 percent.


Over the next couple of weeks, quarterly reports on fourth-quarter profits are expected to come in above the previous quarter’s lackluster results, but analysts’ current estimates are down sharply from where they were in October. Quarterly earnings are expected to grow by 2.8 percent, according to Thomson Reuters data.


German data showed industrial orders fell more than forecast in November because of a sharp drop in demand from abroad, reinforcing concerns that Europe’s largest economy may have contracted in the fourth quarter of 2012.


“I’m surprised futures are holding up, given the relative disappointment that German data showed, but I think all eyes are on the beginning of earnings season,” said Kim Forrest, senior equity research analyst at Fort Pitt Capital Group in Pittsburgh.


European shares were mixed after the German report, with the DAX index in Frankfurt down 0.1 percent and the CAC 40 in Paris up 0.5 percent in afternoon trading.


Monsanto shares rose 3.5 percent after the world’s largest seed company raised its earnings outlook for fiscal 2013 and posted strong first-quarter results.


Shares of the restaurant-chain operator Yum Brands fell 4.6 percent. On Monday the company, which owns KFC, warned that sales in China, its largest market, shrank more than expected in the fourth quarter.


Vodafone shares rose almost 3 percent in London after its American partner in the joint venture Verizon Wireless said it would be “feasible” to buy out the British group.


Sears Holdings shares were 1.9 percent lower a day after the company said its chief executive would step down for family health reasons.


GameStop shares fell 6.8 percent after it reported sales for the holiday season and cut its guidance.


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The New Old Age Blog: Who Should Receive Organ Transplants?

Joe Gammalo had been contending with pulmonary fibrosis, a scarring of the lungs, for more than a decade when he came to the Cleveland Clinic in 2008 seeking a lung transplant.

“It had gotten to the point where I was on oxygen all the time and in a wheelchair,” he told me in an interview. “I didn’t expect to live.”

Lung transplants are a dicey proposition, involving a huge surgical procedure, arduous follow-up, the lifelong use of potent immunosuppressive drugs and high rates of serious side effects. “It’s not like taking out an appendix,” said Dr. Marie Budev, the medical director of the clinic’s lung transplant program.

Only 50 to 57 percent of all recipients live for five years, she noted, and they will still die of their disease. But there’s no other treatment for pulmonary fibrosis.

Some medical centers would have turned Mr. Gammalo away. Because survival rates are even lower for older patients, guidelines from the International Society for Heart and Lung Transplantation caution against lung transplants for those over 65, though they set no age limit.

But “we are known as an aggressive, high-risk center,” said Dr. Budev. So Mr. Gammalo was 66 when he received a lung; his newly found buddy, Clyde Conn, who received the other lung from the same donor, was 69.

You can’t mistake the trend: A graying population and revised policies determining who gets priority for donated organs, have led to a rising proportion of older adults receiving transplants.

My colleague Judith Graham has reported on the increase in heart transplants, but the pattern extends to other organs, too.

The number of kidney transplants performed annually on adults over 65 tripled between 1998 and last year, according to data from the Scientific Registry of Transplant Recipients. In 2001, 7.4 percent of liver transplant recipients were over 65; last year, that rose to 13 percent.

The rise in elderly lung transplant candidates is particularly dramatic because, since 2005, a “lung allocation score” puts those at the highest mortality risk, rather than those who’ve waited longest, at the top of the list.

In 2001, about 3 percent of those on the wait list and of those transplanted were over 65; last year, older patients represented almost 18 percent of wait-listed candidates and more than a quarter of transplant recipients. (Medicare pays for the surgery, though patients face co-pays and considerable out-of-pocket costs, including for drugs and travel.)

The debate has grown, too: When the number of adults awaiting transplants keeps growing, but organ donations stay flat, is it desirable or even ethical that an increasing proportion of recipients are elderly?

Dr. Budev, who estimated that a third of her program’s patients are over 65, votes yes. As long as a program selects candidates carefully, “how can you deny them a therapy?” she asked. So the Cleveland Clinic has no age limit. “We feel that everyone should have a chance.”

At the University of Michigan, by contrast, the age limit remains 65, though Dr. Kevin Chan, the transplant program’s medical director, acknowledged that some fit older patients get transplanted.

“You can talk about this all day — it’s a tough one,” Dr. Chan said. Younger recipients have greater physiologic reserve to aid in the arduous recovery; older ones face higher risk of subsequent kidney failure, stroke, diabetes and other diseases, and, of course, their lifespans are shorter to begin with.

Donated lungs, fragile and prone to injury, are a particularly scarce commodity. Last year, surgeons performed 16,055 kidney transplants, 5,805 liver transplants and 1,949 heart transplants. Only1,830 patients received lung transplants.

“What if there’s a 35-year-old on a ventilator who needs the lung just as much?” Dr. Chan said. “Why should a 72-year-old possibly take away a lung from a 35-year-old?” Yet, he acknowledged, “it’s easy to look at the statistics and say, ‘Give the lungs to younger patients.’ At the bedside, when you meet this patient and family, it’s a lot different.”

These questions about who deserves scarce resources — those most likely to die without them? or those most likely to live longer with them? — will persist as the population ages. They’re also likely to arise when the International Society for Heart and Lung Transplantation begins working towards revised guidelines this spring. (I’d also like to hear your take, below.)

Lots of 65- and 75-year-olds are very healthy. Yet transplants themselves can cause harm and there’s no backup, like dialysis. Without the transplant, they die. But when the transplant goes wrong, they also die.

More than four years post-transplant, the Cleveland Clinic’s “lung brothers” are success stories. Mr. Conn, who lives near Dayton, Ohio, can’t walk very far or lift more than 10 pounds, but he works part time as a real-estate appraiser and enjoys cruises with his wife.

Mr. Gammalo, a onetime musician, has developed diabetes, like nearly half of all lung recipients. But he went onstage a few weeks back to sing “Don’t Be Cruel” with his son’s rock band, “a highlight of both our lives,” he said.

Yet when I asked Mr. Conn, now 73, how he felt about having priority over a younger but healthier person, he paused. “It’s a good question,” he said, to which he had no answer.


Paula Span is the author of “When the Time Comes: Families With Aging Parents Share Their Struggles and Solutions.”

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